As a relatively new user of Fluent, I was hoping that somebody would be able to explain the basics of creating unsteady flow in Fluent. I am attempting to model blood flow through various geometries.

Paul, Go to the main menu..select Define>>Solver, in this panel you can set your solver to unsteady...BUT..dont forget that blood is NON-NEWTONIAN fluid, where the NS slover cannot be applied accurately..good luck

Paul, if you want some more help you can look into help>>basic physical models>>time dependent simulations.you will get all the inputs you need for modelling unsteady flow.