The Respiratory and Aerosol Dynamics Lab in the Virginia Commonwealth
University Department of Mechanical Engineering invites applications from
highly motivated individuals for a postdoctoral position. This position is
supported by an FDA sponsored project that seeks to advance the development of
an existing CFD model of orally inhaled drug products that can account for
inhaler characteristics, drug physicochemical properties, and physiological
parameters on local and regional drug deposition throughout the airways. In
this study, an existing CFD model will be extended to predict deposition
throughout the lungs (TB and alveolar regions) with the inclusion of wall
motion. Models will be developed that can account for intersubject variability
in terms of both geometry and inhalation waveforms. An emphasis of the current
project will be on comparing both in vitro experiments and CFD predictions with
available in vivo studies in terms of lung drug delivery and drug depositional
distribution within the airways.
In addition to excellent academic and publication records, applicants should
have experience in computational modeling, advanced mesh generation in complex
geometries, and multiphase transport.
To apply, please send a CV, transcript copy, list of three references, and a
cover letter summarizing relevant experience to Dr. P. Worth Longest at
pwlongest@vcu.edu.
The Mechanical Engineering Department at VCU offers a highly interdisciplinary
research experience, which is essential for the study of multiphase respiratory
dynamics. Areas of expertise include transport modeling, computational fluid
dynamics, life science engineering, and pharmaceutics. This project is being
performed in collaboration with the VCU Department of Pharmaceutics, which is
located on the VCU Medical Campus. The VCU Department of Pharmaceutics is
widely recognized for its Aerosol Research Group, which specializes in the area
of respiratory drug delivery, and organizes the international RDD Conference
series each year.
VCU is an Equal-Opportunity Affirmative Action Employer. Women, minorities and
persons with disabilities are strongly encouraged to apply.
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