New Workstation Build
 

I am looking to update my CFD workstation. We are using ANSYS exclusively with mainly running Fluent and we are on 17.0, but will be going to 18.0 when it is released.

CPU: 2x E5-2660 V4
MOBO: ASUS Z10PE-D16 WS
ECC: Crucial 128gb DDR4 2133 (4x32gb) **will upgrade to another 128gb later this year**
GPU: Quadro M4000 and would like to add a Tesla K20 later in the year
Cooling: Water Cooling for the CPU's

What do you think? Anything that is better for the sameish price?

A few things: you should use DDR4-2400. And get the additional 4x32GB RAM as soon as possible, the workstation will run much slower than its full potential with only 4 DIMMs.
Water cooling is definitely unnecessary for these CPUs.
You might consider the E5-2650v4 CPUs instead. They only have 12 Cores (how many parallel licenses do you have?) but a slightly higher turbo frequency with all cores active. And they are cheaper.

Thank you very much on your reply! The reason I went with the 2133 MHz ram is from the motherboard. Am I mistaken and it can actually handle 2400 MHz? Also looks like I might go with your CPU choice and move up to 4 more 32 GB sticks.

We have the ANSYS HPC license so core numbers aren't an issue :D

As long as you use a maximum of 8 DIMMs this motherboard allows DDR4-2400. Refer to the information on their website and the surprisingly recent memory QVL http://dlcdnet.asus.com/pub/ASUS/mb/...726.1482645711
Most motherboards that were originally released for Haswell-EP processors (v3) support Broadwell-EP (v4) and higher memory speeds after a bios update.

Thanks for all your help :D