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Job Record #16995
TitlePhD student in Mechanical Engineering
CategoryJob in Academia
EmployerLiverpool John Moores University
LocationUnited Kingdom, Liverpool
InternationalYes, international applications are welcome
Closure DateWednesday, March 31, 2021
***N.B. INTERNATIONL APPLICATIONS ARE WELCOMED, BUT THE APPLICANTS MUST BE UK RESIDENT AND ALREADY IN THE UK*** Atherosclerosis is a disease in large arteries which is caused by an accumulation of lipid-laden macrophages (form cells) and smooth muscle cells on the inner lining of blood vessels. The thickening and hardening of the arterial wall are followed by a rupture of soft lipid plaques into the blood stream, resulting in heart attack and stroke. Cardiovascular disease (CVD), which includes heart attack, stroke and all other disease of the heart and circulation, is the world’s biggest killer, which claims an estimated 16 million lives annually. To prevent this deadly disease, it is important to understand the initiation and growth mechanism of atheroma as well as the main cause of arterial plaque rupture. The periodic transition to/from turbulence of blood flow in arteries at subcritical Reynolds numbers is strongly influencing the development of some of the diseases and subsequent arterial plaque rupture. However, existing theories are unable to explain the observation that the wall shear stress in unsteady flows significantly lags behind turbulence response. The aim of this project is to investigate effect of various pulsatile parameters on flow behaviour in some large veins in order to understand the initiation and growth mechanism of atheroma as well as the main cause of arterial plaque rupture. This process will be simulated using DNS (Direct Numerical Simulation) and LES (Large Eddy Simulation) accompanied by experimental data which will be obtained in collaboration with the project partner. Candidate. The successful candidate should have, or expect to have an excellent first degree with strong background in engineering, applied mathematics or physics. Funding Notes. The studentship is for full time study based in LJMU and will start as soon as a suitable candidate is found. The studentship provides full tuition fees and a tax-free maintenance allowance. Informal enquiries are welcome and should be addressed to Dr Mehdi Seddighi on
Contact Information:
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NameMehdi Seddighi
Email ApplicationYes
AddressDr Mehdi Seddighi
School of Engineering
Liverpool John Moores University
Liverpool, L3 3AF
Record Data:
Last Modified23:15:20, Wednesday, February 24, 2021

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